CURRENT TRENDS OF EXTENDED-SPECTRUM BETA-LACTAMASES PRODUCING MICROORGANISMS

CURRENT TRENDS OF EXTENDED-SPECTRUM BETA-LACTAMASES PRODUCING MICROORGANISMS

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CURRENT TRENDS OF EXTENDED-SPECTRUM BETA-LACTAMASES PRODUCING MICROORGANISMS



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TABLE OF CONTENTS
CHAPTER ONE
1.0 Introduction
CHAPTER TWO
2.1 Extended-spectrum 𝛽-lactamases
2.2 Beta Lactams
2.3 Classification of Beta-Lactamases
2.3.1 Group I (Ambler Class C) beta-lactamases (also known as AmpC enzymes).
2.3.2 Group 2 (Ambler Class A) enzymes
2.3.3 Group 3 (Ambler Class B) enzymes
2.4 Types of ESBLs
2.5 ESBL Producing Organisms
2.5.1 Enterobacteriaceae
2.5.2 E.coli and Klebsiella species
2.5.3 Pseudomonas aeruginosa
2.5.4 Acinetobacter Species
2.6 Prevention and Control Management of ESBL
2.7 Treatment and Management of ESBL Infection
CHAPTER THREE
3.1 Risk Factors for Colonization and Infection with Extended Spectrum Beta-
lactamase Producers
3.2 Risk Factors for Extended Spectrum Beta-lactamase Acquired in Adults
3.3 Risk Factors for Extended Spectrum Beta-lactamase Acquired in Children
3.4 Dissemination of ESBL
3.4.1 Clonal expansion
3.4.2 Horizontal dissemination
3.5 Persistence of ESBL
CHAPTER FOUR
4.0 Epidemiology of Extended Spectrum Lactamase
4.1 Epidemiology of Extended Spectrum Lactamase in South and Central America
4.2 Epidemiology of Extended Spectrum Lactamase in North America
4.3 Epidemiology of Extended Spectrum Lactamase in Europe
4.4 Epidemiology of Extended Spectrum Lactamase in Africa
4.5 Epidemiology of Extended Spectrum Lactamase in Middle East
4.6 Epidemiology of Extended Spectrum Lactamase in Australia
4.7 Epidemiology of Extended Spectrum Lactamase in Asia
CHAPTER FIVE
Conclusion
References

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